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Bioequivalence Analysis of Terazosin Hydrochloride Tablets Based on Parallel Artificial Membrane Permeability Analysis

Parallel artificial membrane permeability analysis (PAMPA) is used to determine the permeability of compounds through concentrated negatively charged phospholipid bilayer barriers. We employed MacroFlux (a scaled-up version of PAMPA) to test the permeation rate of terazosin hydrochloride (TH) tablet...

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Main Authors: Jianzhao Niu, Hanhan Huang, Ming Ji, Wenjing Zhang, Yin Huang, Lingyun Ma, Baolian Wang, Qian Liu
Format: Artigo
Language:Inglês
Published: MDPI AG 2024-08-01
Series:Pharmaceuticals
Subjects:
terazosin hydrochloride tablets
bioequivalence
flux
permeability
dissolution profiles
Online Access:https://www.mdpi.com/1424-8247/17/8/1024
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