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Crystal structure of glycogen debranching enzyme and insights into its catalysis and disease-causing mutations

Debranching of glycogen is an important step in its use as an energy source. Here, the authors describe the crystal structures of glycogen debranching enzyme alone and in complex with oligosaccharides and provide molecular insights into the function, and into associated diseases.

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書誌詳細
主要な著者: Liting Zhai, Lingling Feng, Lin Xia, Huiyong Yin, Song Xiang
フォーマット: Artigo
言語:Inglês
出版事項: Nature Portfolio 2016-04-01
シリーズ:Nature Communications
オンライン・アクセス:https://doi.org/10.1038/ncomms11229
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