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Altered gut microbiota of obesity subjects promotes colorectal carcinogenesis in miceResearch in context

Summary: Background: Obesity is a risk factor for colorectal cancer (CRC). The role of gut microbiota in mediating the cancer-promoting effect of obesity is unknown. Methods: Azoxymethane (AOM)-treated, ApcMin/+ and germ-free mice were gavaged with feces from obese individuals and control subjects...

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Hlavní autoři: Xing Kang, Siu-Kin Ng, Changan Liu, Yufeng Lin, Yunfei Zhou, Thomas N.Y. Kwong, Yunbi Ni, Thomas Y.T. Lam, William K.K. Wu, Hong Wei, Joseph J.Y. Sung, Jun Yu, Sunny H. Wong
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2023-07-01
Edice:EBioMedicine
Témata:
Obesity
Microbiota
Colorectal cancer
Pro-inflammation
Gut barrier
On-line přístup:http://www.sciencedirect.com/science/article/pii/S2352396423002359
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