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nc886 noncoding RNA regulates hepatitis B virus replication via PKR-dependent eIF2α phosphorylation

Objective(s)Hepatitis B virus (HBV) replication is tightly controlled by host stress and innate immune pathways. The small noncoding RNA nc886 (vtRNA2-1) is a known endogenous inhibitor of protein kinase R (PKR), but its role in HBV biology remains unclear. This study aimed to define the function of...

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Bibliografiske detaljer
Principais autores: Zahra Zahid Piracha, Umar Saeed
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2026-03-01
Serier:Frontiers in Cellular and Infection Microbiology
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Online adgang:https://www.frontiersin.org/articles/10.3389/fcimb.2026.1742078/full
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