Preclinical in vitro screening of newly synthesised amidino substituted benzimidazoles and benzothiazoles

Newly synthesised benzimidazole/benzotiazole derivatives bearing amidino, namely 3,4,5,6-tetrahydropyrimidin-1-ium chloride, substituents have been evaluated for their potential antitumor activity in vitro. Compounds and standard drugs (doxorubicin, staurosporine and vandetanib) were tested on three...

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Үндсэн зохиолчид:	Livio Racané, Maja Cindrić, Ivo Zlatar, Tatjana Kezele, Astrid Milić, Karmen Brajša, Marijana Hranjec
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Taylor & Francis Group 2021-01-01
Цуврал:	Journal of Enzyme Inhibition and Medicinal Chemistry
Нөхцлүүд:	amidines benzimidazoles benzotiazoles 2d and 3d in vitro cytotoxicity assay apoptotic activity adme
Онлайн хандалт:	http://dx.doi.org/10.1080/14756366.2020.1850711
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!