Quantifying cell fate change under different stochastic gene activation frameworks

Abstract Gene transcription is a stochastic process characterized by fluctuations in mRNA levels of the same gene in isogenic cell populations. A central question in single‐cell studies is how to map transcriptional variability to phenotypic differences between isogenic cells. We introduced a measur...

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Hlavní autoři:	Xinxin Chen, Ying Sheng, Liang Chen, Moxun Tang, Feng Jiao
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Wiley 2025-03-01
Edice:	Quantitative Biology
Témata:	cell fate change mRNA distribution statistical transcription threshold stochastic gene transcription transcription noise
On-line přístup:	https://doi.org/10.1002/qub2.82
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