Combining laser microdissection and microRNA expression profiling to unmask microRNA signatures in complex tissues

Neglecting tissue heterogeneity during the analysis of microRNA (miRNA) levels results in average signals from an unknown mixture of different cell types that are difficult to interpret. Here we demonstrate the technical requirements needed to obtain high-quality, quantitative miRNA expression infor...

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Bibliografiska uppgifter

Huvudupphov:	Susanna Skalicky, Peter J Zwiers, Timara Kuiper, Elisabeth Schraml, Matthias Hackl, Grietje Molema
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	Taylor & Francis Group 2019-12-01
Serie:	BioTechniques
Ämnen:	biomarker discovery drug discovery laser microdissection (LMD) microRNA profiling tissue complexity tumor microenvironment
Länkar:	https://www.future-science.com/doi/10.2144/btn-2019-0032
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