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SHP2 Nuclear/Cytoplasmic Trafficking in Granulosa Cells Is Essential for Oocyte Meiotic Resumption and Maturation

Src-homology-2-containing phosphotyrosine phosphatase (SHP2), a classic cytoplasmic protein and a major regulator of receptor tyrosine kinases and G protein-coupled receptors, plays a significant role in preimplantation embryo development. In this study, we deciphered the role of SHP2 in the somatic...

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Autors principals: Muhammad Idrees, Vikas Kumar, Myeong-Don Joo, Niaz Ali, Keun-Woo Lee, Il-Keun Kong
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2021-01-01
Col·lecció:Frontiers in Cell and Developmental Biology
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Accés en línia:https://www.frontiersin.org/articles/10.3389/fcell.2020.611503/full
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