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A Reappraisal of the Effects of L-type Ca2+ Channel Blockers on Store-Operated Ca2+ Entry and Heart Failure

Abstract Dihydropyridines such as amlodipine are widely used as antihypertensive agents, being prescribed to ∼70 million Americans and >0.4 billion adults worldwide. Dihydropyridines block voltage-gated Ca2+ channels in resistance vessels, leading to vasodilation and a reduction in blood pressure. V...

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Hlavní autoři: Gary S Bird, Diane D’Agostin, Safaa Alsanosi, Stefanie Lip, Sandosh Padmanabhan, Anant B Parekh
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2023-01-01
Edice:Function
On-line přístup:https://journals.physiology.org/doi/10.1093/function/zqad047
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