Mycobacteria trehalose dimycolate interactions with host Mincle remodel blood-brain barrier junctions for brain invasion

Summary: Tuberculous meningitis is unique among bacterial meningitides because it occurs in two temporally separated steps: mycobacteria first invade the brain, then form infected macrophage aggregates called Rich foci, which later erode the meninges. Here, using transparent zebrafish larvae, we det...

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Hlavní autoři:	Megan I. Hayes, Sumedha Ravishankar, Jonathan K. Shanahan, Adam J. Fountain, Lalita Ramakrishnan, Cressida A. Madigan
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2025-12-01
Edice:	Cell Reports
Témata:	CP: microbiology CP: neuroscience
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S2211124725014330
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