Clustered ARPE-19 cells distinct in mitochondrial membrane potential may play a pivotal role in cell differentiation

Abstract Age-related macular degeneration (AMD) is associated with the dysfunction and degeneration of retinal pigment epithelium (RPE) cells. Here, we examined how the formation and expansions of cell clusters are regulated by the differentiation of the RPE　cells. In this study, ARPE-19 cells were...

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Hlavní autoři:	Takafumi Miyatani, Hiroshi Tanaka, Kosaku Numa, Asako Uehara, Yohei Otsuki, Junji Hamuro, Shigeru Kinoshita, Chie Sotozono
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Portfolio 2024-09-01
Edice:	Scientific Reports
Témata:	Retinal pigment epithelial (RPE) cell differentiation Cell cluster formation Mitochondrial membrane potential (MMP) Electron transport chain (ETC) complex I inhibitor
On-line přístup:	https://doi.org/10.1038/s41598-024-73145-w
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