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Pilot Study of Anti-Th2 Immunotherapy for the Treatment of Breast Cancer-Related Upper Extremity Lymphedema

Recent studies suggest that Th2 cells play a key role in the pathology of secondary lymphedema by elaborating cytokines such as IL4 and IL13. The aim of this study was to test the efficacy of QBX258, a monoclonal IL4/IL13 neutralizing antibody, in women with breast cancer–related lymphedema (BCRL)....

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Principais autores: Babak J. Mehrara, Hyeung Ju Park, Raghu P. Kataru, Jacqueline Bromberg, Michelle Coriddi, Jung Eun Baik, Jinyeon Shin, Claire Li, Michele R. Cavalli, Elizabeth M. Encarnacion, Meghan Lee, Kimberly J. Van Zee, Elyn Riedel, Joseph H. Dayan
Formato: Artigo
Idioma:Inglês
Publicado: MDPI AG 2021-09-01
Series:Biology
Assuntos:
lymphedema
immunotherapy
skin
Th2 inflammation
breast cancer
keratinocytes
Acceso en liña:https://www.mdpi.com/2079-7737/10/9/934
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