Pharmaco-genetic therapeutics targeting parvalbumin neurons attenuate temporal lobe epilepsy

Temporal lobe epilepsy (TLE) is the most common type of epilepsy and is often medically refractory. Previous studies suggest that selective pharmaco-genetic inhibition of pyramidal neurons has therapeutic value for the treatment of epilepsy, however there is a risk of disrupting normal physical func...

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מידע ביבליוגרפי

Principais autores:	Ying Wang, Jiao Liang, Liying Chen, Yating Shen, Junli Zhao, Cenglin Xu, Xiaohua Wu, Heming Cheng, Xiaoying Ying, Yi Guo, Shuang Wang, Yudong Zhou, Yi Wang, Zhong Chen
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Elsevier 2018-09-01
סדרה:	Neurobiology of Disease
נושאים:	Temporal lobe epilepsy Pharmaco-genetic Parvalbumin neurons Pyramidal neurons
גישה מקוונת:	http://www.sciencedirect.com/science/article/pii/S0969996118301815
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