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Mitochondrial temperature-responsive drug delivery reverses drug resistance in lung cancer

Reversal of cancer drug resistance remains a critical challenge in chemotherapy. Mitochondria-targeted drug delivery has been suggested to mitigate drug resistance in cancer. To overcome the intrinsic limitations in conventional mitochondrial targeting strategies, we develop mitochondrial temperatur...

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Principais autores: Lifo Ruan, Jun Chen, Chuanchao Du, Huiru Lu, Jiayu Zhang, Xiaomeng Cai, Rui Dou, Wenchu Lin, Zhifang Chai, Guangjun Nie, Yi Hu
Formato: Artigo
Idioma:Inglês
Publicado em: KeAi Communications Co., Ltd. 2022-07-01
coleção:Bioactive Materials
Assuntos:
Mitochondrial temperature
Thermoresponsive
Drug delivery
Drug resistance
Nanomedicines
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2452199X2100517X
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