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Pan-cancer single cell transcriptomic clustering reveals heterogeneous CD8+ exhausted T cell populations with different immune checkpoint inhibitor responses

In most cancers, T lymphocytes comprise an essential cellular component of the non-neoplastic microenvironment, where they have the capacity to both suppress and support tumor growth. One specialized T lymphocyte population is the CD8+ exhausted T cell, which has been intensely studied as an actiona...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Rui Mu, Rasha Barakat, David H. Gutmann
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Taylor & Francis Group 2025-12-01
Saila:OncoImmunology
Gaiak:
Sarrera elektronikoa:https://www.tandfonline.com/doi/10.1080/2162402X.2025.2540504
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