Human Pluripotent Stem Cell-Based Models for Hirschsprung Disease: From 2-D Cell to 3-D Organoid Model

Hirschsprung disease (HSCR) is a complex congenital disorder caused by defects in the development of the enteric nervous system (ENS). It is attributed to failures of the enteric neural crest stem cells (ENCCs) to proliferate, differentiate and/or migrate, leading to the absence of enteric neurons i...

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Hlavní autoři:	Kathy Nga-Chu Lui, Elly Sau-Wai NGAN
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	MDPI AG 2022-10-01
Edice:	Cells
Témata:	Hirschsprung disease induced pluripotent stem cells disease modeling enteric nervous system colonic organoids
On-line přístup:	https://www.mdpi.com/2073-4409/11/21/3428
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