A stability indicating UPLC method development and validation for the simultaneous estimation of nateglinide and metformin hydrochloride in bulk and tablet dosage form

Abstract Background Nateglinide and metformin HCl are used in combination for the treatment of type 2 diabetes. A simple, sensitive and reliable UPLC method was developed for simultaneous estimation of nateglinide and metformin HCl using Phenomenox C18 (50*2.1 mm, 3.5 µm) column at ambient temperatu...

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Hauptverfasser:	Ashritha Narikimalli, Rajitha Galla
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	SpringerOpen 2023-06-01
Schriftenreihe:	Future Journal of Pharmaceutical Sciences
Schlagworte:	UPLC Method development Validation Forced degradation studies Nateglinide Metformin HCl
Online-Zugang:	https://doi.org/10.1186/s43094-023-00503-2
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