Codon decoding by orthogonal tRNAs interrogates the in vivo preferences of unmodified adenosine in the wobble position

The in vivo codon decoding preferences of tRNAs with an authentic adenosine residue at position 34 of the anticodon, the wobble position, are largely unexplored because very few unmodified A34 tRNA genes exist across the three domains of life. The expanded wobble rules suggest that unmodified adenos...

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Hauptverfasser:	Margaret A. Schmitt, Jillyn M. Tittle, John D. Fisk
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2024-04-01
Schriftenreihe:	Frontiers in Genetics
Schlagworte:	tRNA modification inosine orthogonal translation machinery sense codon reassignment wobble translation
Online-Zugang:	https://www.frontiersin.org/articles/10.3389/fgene.2024.1386299/full
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