Heterogeneity of Human Neutrophil CD177 Expression Results from CD177P1 Pseudogene Conversion.
Most humans harbor both CD177neg and CD177pos neutrophils but 1-10% of people are CD177null, placing them at risk for formation of anti-neutrophil antibodies that can cause transfusion-related acute lung injury and neonatal alloimmune neutropenia. By deep sequencing the CD177 locus, we catalogued CD...
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| Glavni autori: | , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Public Library of Science (PLoS)
2016-05-01
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| Serija: | PLoS Genetics |
| Online pristup: | http://europepmc.org/articles/PMC4882059?pdf=render |
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