PARP inhibitors: review of mechanisms of action and BRCA1/2 mutation targeting
Poly(ADP-ribose) polymerases have shown true promise in early clinical studies due to reported activity in BRCA-associated cancers. PARP inhibitors may represent a potentially important new class of chemotherapeutic agents directed at targeting cancers with defective DNA-damage repair. In order to w...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Termedia Publishing House
2017-02-01
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| Schriftenreihe: | Menopause Review |
| Schlagworte: | |
| Online-Zugang: | https://www.termedia.pl/PARP-inhibitors-review-of-mechanisms-of-action-and-BRCA1-2-mutation-targeting,4,29355,1,1.html |
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