Widespread Evolution of Molecular Resistance to Snake Venom α-Neurotoxins in Vertebrates

Venomous snakes are important subjects of study in evolution, ecology, and biomedicine. Many venomous snakes have alpha-neurotoxins (α-neurotoxins) in their venom. These toxins bind the alpha-1 nicotinic acetylcholine receptor (nAChR) at the neuromuscular junction, causing paralysis and asphyxia. Se...

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Detalles Bibliográficos

Principais autores:	Muzaffar A. Khan, Daniel Dashevsky, Harald Kerkkamp, Dušan Kordiš, Merijn A. G. de Bakker, Roel Wouters, Jory van Thiel, Bianca op den Brouw, Freek J. Vonk, R. Manjunatha Kini, Jawad Nazir, Bryan G. Fry, Michael K. Richardson
Formato:	Artigo
Idioma:	Inglês
Publicado:	MDPI AG 2020-10-01
Series:	Toxins
Assuntos:	evolutionary arms race Elapidae venom resistance nicotinic acetylcholine receptor (nAChR) CHRNA1
Acceso en liña:	https://www.mdpi.com/2072-6651/12/10/638
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