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Tissue environment, not ontogeny, defines murine intestinal intraepithelial T lymphocytes

Tissue-resident intestinal intraepithelial T lymphocytes (T-IEL) patrol the gut and have important roles in regulating intestinal homeostasis. T-IEL include both induced T-IEL, derived from systemic antigen-experienced lymphocytes, and natural T-IEL, which are developmentally targeted to the intesti...

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Bibliografske podrobnosti
Principais autores: Alejandro J Brenes, Maud Vandereyken, Olivia J James, Harriet Watt, Jens Hukelmann, Laura Spinelli, Dina Dikovskaya, Angus I Lamond, Mahima Swamy
Format: Artigo
Jezik:Inglês
Izdano: eLife Sciences Publications Ltd 2021-09-01
Serija:eLife
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Online dostop:https://elifesciences.org/articles/70055
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