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RNA-binding protein p54nrb/NONO potentiates nuclear EGFR-mediated tumorigenesis of triple-negative breast cancer

Abstract Nuclear-localized epidermal growth factor receptor (EGFR) highly correlates with the malignant progression and may be a promising therapeutic target for breast cancer. However, molecular mechanisms of nuclear EGFR in triple-negative breast cancer (TNBC) have not been fully elucidated. Here,...

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Autori principali: Mengqin Shen, Ruixue Zhang, Wenzhi Jia, Zongping Zhu, Li Zhao, Gang Huang, Jianjun Liu
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2022-01-01
Serie:Cell Death and Disease
Accesso online:https://doi.org/10.1038/s41419-021-04488-9
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