2‐Hydroxyisobutyrylation and Phosphorylation Crosstalk Guides Metastasis Prediction and Immunotherapy in Esophageal Squamous Cell Carcinoma

ABSTRACT Posttranslational modification (PTM) is pivotal in cancer progression. However, the mechanisms, biological function, and clinical significance underlying PTM crosstalk are unclear. Here, we performed systematic analyses of 2‐hydroxyisobutyrylation (Khib), phosphoproteomic, proteomic, and tr...

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Päätekijät:	Junyi Li, Shujun Li, Xiaomei Yu, Qier Mu, Maowen Luo, Yuzhen Wang, Zhichao Liu, Chengwei Gu, Jiaxi Chen, Wangcheng He, Tong Yang, Yan He, Xiaoya Pei, Mao Lin, Zhigang Li, Jun Liu, Baosheng Zhao, Fan Zhang, Jinbao Liu, Bin Li, Wenwen Xu
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Wiley 2026-07-01
Sarja:	MedComm
Aiheet:	esophageal squamous cell carcinoma immunotherapy combination metastasis plasma biomarker PTM crosstalk
Linkit:	https://doi.org/10.1002/mco2.70815
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