Reactive Oxygen Species in the Adverse Outcome Pathway Framework: Toward Creation of Harmonized Consensus Key Events

Reactive oxygen species (ROS) and reactive nitrogen species (RNS) are formed as a result of natural cellular processes, intracellular signaling, or as adverse responses associated with diseases or exposure to oxidizing chemical and non-chemical stressors. The action of ROS and RNS, collectively refe...

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Główni autorzy:	Shihori Tanabe, Jason O’Brien, Knut Erik Tollefsen, Youngjun Kim, Vinita Chauhan, Carole Yauk, Elizabeth Huliganga, Ruthann A. Rudel, Jennifer E. Kay, Jessica S. Helm, Danielle Beaton, Julija Filipovska, Iva Sovadinova, Natalia Garcia-Reyero, Angela Mally, Sarah Søs Poulsen, Nathalie Delrue, Ellen Fritsche, Karsta Luettich, Cinzia La Rocca, Hasmik Yepiskoposyan, Jördis Klose, Pernille Høgh Danielsen, Maranda Esterhuizen, Nicklas Raun Jacobsen, Ulla Vogel, Timothy W. Gant, Ian Choi, Rex FitzGerald
Format:	Artigo
Język:	Inglês
Wydane:	Frontiers Media S.A. 2022-07-01
Seria:	Frontiers in Toxicology
Hasła przedmiotowe:	adverse outcome pathway (AOP) oxidative stress reactive nitrogen species (RNS) disease reactive oxygen species (ROS)
Dostęp online:	https://www.frontiersin.org/articles/10.3389/ftox.2022.887135/full
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