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Personalized polygenic profiling based on the genetic architecture of lipid metabolism in the Russian population

ObjectiveElevated cholesterol levels are associated with the risk of the most socially significant cardiovascular diseases, such as atherosclerosis, ischemic heart disease, and myocardial infarction.MethodsIn this study, we sought to study the genetic architecture of lipid metabolism by conducting g...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Aleksandra Mamchur, Maria Bruttan, Veronika Daniel, Daria Kashtanova, Elena Zelenova, Irina Dzhumaniiazova, Mikhail Ivanov, Lorena Matkava, Olga Blinova, Sergey Mitrofanov, Liliya Golubnikova, Naiana Kumar, Ekaterina Maralova, Andrey Shingaliev, Marat Ezhov, Aleksey Meshkov, Uliana Chubykina, Olga Pogorelova, Mariia Tripoten, Tatyana Balahonova, Alexandra Viskova, Madina Komarova, Timur Gurtsiev, Natalia Gomyranova, Yulia Vorobeva, Anastasia Hotuleva, Maria Kolyaskina, Vladimir Yudin, Valentin Makarov, Anton Keskinov, Lyudmila Kuzmina, Sergey Boytsov, Sergey Yudin, Veronika Skvortsova
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2026-06-01
Schriftenreihe:Frontiers in Cardiovascular Medicine
Schlagworte:
cholesterol
dyslipidemia
GWAS
HDL
LDL
polygenic score (PGS)
Online-Zugang:https://www.frontiersin.org/articles/10.3389/fcvm.2026.1707598/full
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