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The CD9/CD81 tetraspanin complex and tetraspanin CD151 regulate α3β1 integrin-dependent tumor cell behaviors by overlapping but distinct mechanisms.

Integrin α3β1 potently promotes cell motility on its ligands, laminin-332 and laminin-511, and this may help to explain why α3β1 has repeatedly been linked to breast carcinoma progression and metastasis. The pro-migratory functions of α3β1 depend strongly on lateral interactions with cell surface te...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Elisabeth Gustafson-Wagner, Christopher S Stipp
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Public Library of Science (PLoS) 2013-01-01
Rangatū:PLoS ONE
Urunga tuihono:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0061834&type=printable
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