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Exploratory analysis of non-linear clozapine dose-concentration relationship in real-life hospital database

IntroductionClozapine (CLO) remains the gold standard for the treatment of drug-resistant schizophrenia. It is commonly accepted that there is a linear relationship between CLO dose and blood concentration, although deviations from this pattern are frequently observed in clinical practice. The aim o...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Anna Mach, Przemysław Bieńkowski, Szymon Tyras, Anna Wnorowska, Maria Radziwoń-Zaleska, Marcin Siwek, Marcin Wojnar
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Frontiers Media S.A. 2026-01-01
Rangatū:Frontiers in Pharmacology
Ngā marau:
Urunga tuihono:https://www.frontiersin.org/articles/10.3389/fphar.2025.1735337/full
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