Neurotrophic Factors NGF, GDNF and NTN Selectively Modulate HSV1 and HSV2 Lytic Infection and Reactivation in Primary Adult Sensory and Autonomic Neurons

Herpes simplex viruses (HSV1 and HSV2) establish latency in peripheral ganglia after ocular or genital infection, and can reactivate to produce different patterns and frequencies of recurrent disease. Previous studies showed that nerve growth factor (NGF) maintains HSV1 latency in embryonic sympathe...

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Principais autores:	Andy A. Yanez, Telvin Harrell, Heather J. Sriranganathan, Angela M. Ives, Andrea S. Bertke
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2017-02-01
coleção:	Pathogens
Assuntos:	herpes simplex virus HSV1 HSV2 primary neurons neurotrophic factors latency reactivation
Acesso em linha:	http://www.mdpi.com/2076-0817/6/1/5
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