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Multivariate Optimization of Chromatographic Conditions for Rapid Simultaneous Quantification of Antidiarrheal Drugs in Formulation Using Surface Response Methodology

A combination of antibiotics and antiprotozoal and antisecretory medicines has been prescribed for the treatment of diarrhea. A rapid, reproducible liquid chromatographic procedure was established for the concurrent analysis of metronidazole (MET), ofloxacin (OFL), and racecadotril (RAC) in suspensi...

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Principais autores: Mahesh Attimarad, Katharigatta Narayanaswamy Venugopala, Muhammad S. Chohan, Pottathil Shinu, Marysheela David, Effren II Plaza Molina, Anroop Balachandran Nair, Nagaraja Sreeharsha, Abdulrahman Ibrahim Altaysan, Abdulmalek Ahmed Balgoname
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2022-04-01
Colecção:Separations
Assuntos:
HPLC
surface response
multivariate optimization
formulation
metronidazole
ofloxacin
Acesso em linha:https://www.mdpi.com/2297-8739/9/5/103
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