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The relationship between iron dyshomeostasis and amyloidogenesis in Alzheimer's disease: Two sides of the same coin

The dysregulation of iron metabolism in Alzheimer's disease is not accounted for in the current framework of the amyloid cascade hypothesis. Accumulating evidence suggests that impaired iron homeostasis is an early event in Alzheimer's disease progression. Iron dyshomeostasis leads to a loss of func...

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Detalles Bibliográficos
Principais autores: Douglas G. Peters, James R. Connor, Mark D. Meadowcroft
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2015-09-01
Series:Neurobiology of Disease
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Acceso en liña:http://www.sciencedirect.com/science/article/pii/S0969996115300280
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