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Atherosclerotic Plaque Fissuration and Clinical Outcomes in Pre-Diabetics vs. Normoglycemics Patients Affected by Asymptomatic Significant Carotid Artery Stenosis at 2 Years of Follow-Up: Role of microRNAs Modulation: The ATIMIR Study

Atherosclerotic plaque instability and rupture in patients with asymptomatic carotid artery stenosis (ACAS) is a leading cause of major adverse cardiac events (MACE). This could be mainly evidenced in patients with pre-diabetes. Indeed, the altered glucose homeostasis and insulin resistance could ca...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Celestino Sardu, Pietro Modugno, Gaetano Castellano, Lucia Scisciola, Michelangela Barbieri, Lella Petrella, Mara Fanelli, Gabriella Macchia, Eugenio Caradonna, Massimo Massetti, Giuseppe Paolisso, Raffaele Marfella
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2021-04-01
Schriftenreihe:Biomedicines
Schlagworte:
atherosclerotic plaque
pre-diabetes
inflammation
microRNAs
metformin therapy
Online-Zugang:https://www.mdpi.com/2227-9059/9/4/401
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