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Mixed Lineage Kinase Domain‐Like Protein (MLKL): From Mechanisms to Therapeutic Opportunities

Abstract Lytic forms of regulated cell death (RCD) rely on the activation and recruitment of executioner proteins. The mixed lineage kinase domain‐like protein (MLKL) acts as the executioner in the necroptosis pathway, transitioning from an inactive to active state through phosphorylation, oligomeri...

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Autors principals: Lijuan Xu, Chunlin Zhuang
Format: Artigo
Idioma:Inglês
Publicat: Wiley 2025-09-01
Col·lecció:Advanced Science
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Accés en línia:https://doi.org/10.1002/advs.202509277
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