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Cofilin-actin rod formation in neuronal processes after brain ischemia.

Functional impairment after brain ischemia results in part from loss of neuronal spines and dendrites, independent of neuronal death. Cofilin-actin rods are covalently linked aggregates of cofilin-1 and actin that form in neuronal processes (neurites) under conditions of ATP depletion and oxidative...

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Autors principals: Seok Joon Won, Angela M Minnella, Long Wu, Claire H Eun, Eric Rome, Paco S Herson, Alisa E Shaw, James R Bamburg, Raymond A Swanson
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2018-01-01
Col·lecció:PLoS ONE
Accés en línia:http://europepmc.org/articles/PMC6191105?pdf=render
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