H1.3 depletion in AML cells prompts H1.2 redistribution, chromatin remodeling and cell cycle defects
Abstract Linker histone H1 variants play critical, yet distinct, roles in chromatin organization and gene regulation. However, their specificity in cancer cells is not well understood. Our previous studies have shown that acute myeloid leukemia (AML) patients who were H3K27me3HIST1-positive exhibite...
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| Principais autores: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMC
2026-05-01
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| coleção: | Epigenetics & Chromatin |
| Assuntos: | |
| Acesso em linha: | https://doi.org/10.1186/s13072-026-00679-w |
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