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Nrf2 and HSF-1 Pathway Activation via Hydroquinone-Based Proelectrophilic Small Molecules Is Regulated by Electrochemical Oxidation Potential

Activation of the Kelch-like ECH-associated protein 1/nuclear factor (erythroid-derived 2)-like 2 and heat-shock protein 90/heat-shock factor-1 signal-transduction pathways plays a central role in combatting cellular oxidative damage and related endoplasmic reticulum stress. Electrophilic compounds...

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Bibliografiset tiedot
Päätekijät: Takumi Satoh, Romain Stalder, Scott R. McKercher, Robert E. Williamson, Gregory P. Roth, Stuart A. Lipton
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Taylor & Francis 2015-07-01
Sarja:ASN Neuro
Linkit:https://doi.org/10.1177/1759091415593294
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