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Effect of the gut microbiota-derived tryptophan metabolite indole-3-acetic acid in pneumonia

Abstract Gut microbiota influence the severity of pneumonia by producing metabolites that enhance systemic and pulmonary immune responses. Preclinical studies suggested that gut microbiota-derived indoles have protective effects against numerous diseases, including influenza and abdominal infections...

Deskribapen osoa

Gorde:
Egile Nagusiak: Robert F. J. Kullberg, Christine C. A. van Linge, Bastiaan W. Haak, Prasanjit S. Paul, Joe M. Butler, Nora Wolff, Tjitske S. R. van Engelen, Jonne J. Sikkens, Marije K. Bomers, Antoine Lefèvre, Olaf L. Cremer, Joris J.T.H. Roelofs, Bruno Sovran, René van den Wijngaard, Alex F. de Vos, Wouter J. de Jonge, Tom van der Poll, W. Joost Wiersinga
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Portfolio 2025-09-01
Saila:Nature Communications
Sarrera elektronikoa:https://doi.org/10.1038/s41467-025-63611-y
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