Fine tuning of the UPR by the ubiquitin ligases Siah1/2.
The endoplasmic reticulum (ER) responds to changes in intracellular homeostasis through activation of the unfolded protein response (UPR). Yet, it is not known how UPR-signaling coordinates adaptation versus cell death. Previous studies suggested that signaling through PERK/ATF4 is required for cell...
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| Principais autores: | , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science (PLoS)
2014-05-01
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| Serier: | PLoS Genetics |
| Online adgang: | http://europepmc.org/articles/PMC4014425?pdf=render |
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