Improved GaLV-TR Glycoproteins to Pseudotype Lentiviral Vectors: Impact of Viral Protease Activity in the Production of LV Pseudotypes

Lentiviral vectors (LVs) are excellent tools for gene transfer into mammalian cells. It is noteworthy that the first gene therapy treatment using LVs was approved for commercialization in 2017. The G glycoprotein from rhabdovirus vesicular stomatitis virus (VSV-G) is the glycoprotein most used to ps...

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Prif Awduron:	Hélio A. Tomás, Daniel A. Mestre, Ana F. Rodrigues, Miguel R. Guerreiro, Manuel J.T. Carrondo, Ana Sofia Coroadinha
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	Elsevier 2019-12-01
Cyfres:	Molecular Therapy: Methods & Clinical Development
Mynediad Ar-lein:	http://www.sciencedirect.com/science/article/pii/S2329050119300804
Tagiau:	Ychwanegu Tag Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!