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Maternal exposure to CeO2NPs derails placental development through trophoblast dysfunction mediated by excessive autophagy activation

Abstract Background The increasing use of cerium dioxide nanoparticles (CeO2NPs) in biomedical field has attracted substantial attention about their potential risks to human health. Recent studies have shown that nanoparticles can induce placental dysfunction and even fetal abortion, but a more deta...

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Principais autores: Zhuxiu Chen, Yanqing Geng, Rufei Gao, Hangtian Zhong, Jun Chen, Xinyi Mu, Xuemei Chen, Yan Zhang, Fangfang Li, Junlin He
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2022-03-01
Serier:Journal of Nanobiotechnology
Fag:
CeO2NPs
Trophoblast
Placenta
Autophagy
HTR-8/SVneo
Online adgang:https://doi.org/10.1186/s12951-022-01334-8
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