MAT2A promotes atherosclerotic plaque vulnerability by mediating epigenetic reprogramming of macrophages

Abstract Atherosclerosis is mediated by circulating monocytes and lesional macrophages through chronic inflammation accompanied by metabolic reprogramming. Although methionine metabolism enhances the proinflammatory capacity of monocytes/macrophages, its role in atherosclerosis remains unclear. Here...

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Hlavní autoři:	Zhuo Du, Pingping Wan, Manyu Du, Song Li, Qiuying Yan, Sibo Sun, Caiying Tang, Ziquan Jiang, Shuang Li, Guoxia Shi, Baixue Miao, Xiaoyu Du, Shilong Li, Shaohong Fang, Chao Wang, Chao Fang, Bo Yu, Jiannan Dai, Ping Sun
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Portfolio 2025-12-01
Edice:	Nature Communications
On-line přístup:	https://doi.org/10.1038/s41467-025-66121-z
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!