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Nuclear envelope-associated lipid droplets are enriched in cholesteryl esters and increase during inflammatory signaling

Abstract Cholesteryl esters (CEs) and triacylglycerols (TAGs) are stored in lipid droplets (LDs), but their compartmentalisation is not well understood. Here, we established a hyperspectral stimulated Raman scattering microscopy system to identify and quantitatively assess CEs and TAGs in individual...

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Bibliografiske detaljer
Principais autores: Ábel Szkalisity, Lauri Vanharanta, Hodaka Saito, Csaba Vörös, Shiqian Li, Antti Isomäki, Teemu Tomberg, Clare Strachan, Ilya Belevich, Eija Jokitalo, Elina Ikonen
Format: Artigo
Sprog:Inglês
Udgivet: Springer Nature 2025-04-01
Serier:The EMBO Journal
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Online adgang:https://doi.org/10.1038/s44318-025-00423-2
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