A Novel C1-Esterase Inhibitor Oxygenator Coating Prevents FXII Activation in Human Blood

The limited hemocompatibility of currently used oxygenator membranes prevents long-term use of artificial lungs in patients with lung failure. To improve hemocompatibility, we developed a novel covalent C1-esterase inhibitor (C1-INH) coating. Besides complement inhibition, C1-INH also prevents FXII...

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Hlavní autoři:	Katharina Gerling, Sabrina Ölschläger, Meltem Avci-Adali, Bernd Neumann, Ernst Schweizer, Christian Schlensak, Hans-Peter Wendel, Sandra Stoppelkamp
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	MDPI AG 2020-07-01
Edice:	Biomolecules
Témata:	ECMO hollow-fiber membranes C1-esterase inhibitor anti-thrombogenic novel coating inflammation
On-line přístup:	https://www.mdpi.com/2218-273X/10/7/1042
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