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SARS-CoV-2 Point Mutation and Deletion Spectra and Their Association with Different Disease Outcomes

ABSTRACT Mutant spectra of RNA viruses are important to understand viral pathogenesis and response to selective pressures. There is a need to characterize the complexity of mutant spectra in coronaviruses sampled from infected patients. In particular, the possible relationship between SARS-CoV-2 mut...

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I tiakina i:
Ngā kaituhi matua: Brenda Martínez-González, María Eugenia Soria, Lucía Vázquez-Sirvent, Cristina Ferrer-Orta, Rebeca Lobo-Vega, Pablo Mínguez, Lorena de la Fuente, Carlos Llorens, Beatriz Soriano, Ricardo Ramos, Marta Cortón, Rosario López-Rodríguez, Carlos García-Crespo, Isabel Gallego, Ana Isabel de Ávila, Jordi Gómez, Luis Enjuanes, Llanos Salar-Vidal, Jaime Esteban, Ricardo Fernandez-Roblas, Ignacio Gadea, Carmen Ayuso, Javier Ruíz-Hornillos, Nuria Verdaguer, Esteban Domingo, Celia Perales
Hōputu: Artigo
Reo:Inglês
I whakaputaina: American Society for Microbiology 2022-04-01
Rangatū:Microbiology Spectrum
Ngā marau:
COVID-19 severity
mutant spectrum
diversity index
mutation
deletion
nsp12 (polymerase)
Urunga tuihono:https://journals.asm.org/doi/10.1128/spectrum.00221-22
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