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Effect of delayed isolation of peripheral blood mononuclear cells on cell viability and functionality

Abstract Background Peripheral blood mononuclear cells (PBMCs) are valuable biomarkers, providing crucial insights into the patients’ immune system. Reliable biobanking of PBMCs is essential to minimize heterogeneity. In multicenter trials, blood sample transportation to central laboratories can inc...

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Principais autores: Sarah Lehle, Simon Völkl, Katharina Seitz, Chloë Goossens, Julius Emons, Matthias Ruebner, Sabrina Uhrig, Philipp Ziegler, Anna-Katharin Theuser, Matthias W. Beckmann, Peter A. Fasching, Hanna Huebner
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2025-03-01
Serier:BMC Immunology
Fag:
PBMCs
Biobanking
Cell viability
Cytotoxicity
Phase IV clinical trial
Online adgang:https://doi.org/10.1186/s12865-025-00701-y
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