Identification and Characterization of Thermostable Y-Family DNA Polymerases η, ι, κ and Rev1 From a Lower Eukaryote, Thermomyces lanuginosus

Y-family DNA polymerases (pols) consist of six phylogenetically separate subfamilies; two UmuC (polV) branches, DinB (pol IV, Dpo4, polκ), Rad30A/POLH (polη), and Rad30B/POLI (polι) and Rev1. Of these subfamilies, DinB orthologs are found in all three domains of life; eubacteria, archaea, and eukary...

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Hauptverfasser:	Alexandra Vaisman, John P. McDonald, Mallory R. Smith, Sender L. Aspelund, Thomas C. Evans, Roger Woodgate
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2021-11-01
Schriftenreihe:	Frontiers in Molecular Biosciences
Schlagworte:	thermostable fungi Y-family DNA polymerases phylogenetic analysis translesion DNA synthesis DNA polymerase eta (polη) DNA polymerase iota (polι)
Online-Zugang:	https://www.frontiersin.org/articles/10.3389/fmolb.2021.778400/full
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