Expression of FRS2 in atypical lipomatous tumor/well-differentiated liposarcoma and dedifferentiated liposarcoma: an immunohistochemical analysis of 182 cases with genetic data

Abstract Background The fibroblast growth factor receptor substrate 2 (FRS2) gene is located close to MDM2 and CDK4 within the 12q13-15 chromosomal region. FRS2 gene was recently found to be consistently amplified in atypical lipomatous tumor (ALT)/well-differentiated liposarcoma (WDL) and dediffere...

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Hlavní autoři:	Wenyi Jing, Ting Lan, Yan Qiu, Ran Peng, Yang Lu, Huijiao Chen, Min Chen, Xin He, Chen Chen, Hongying Zhang
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2021-10-01
Edice:	Diagnostic Pathology
Témata:	Atypical lipomatous tumor Well-differentiated liposarcoma Dedifferentiated liposarcoma Immunohistochemistry FRS2
On-line přístup:	https://doi.org/10.1186/s13000-021-01161-9
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