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RNA-based therapies for colorectal cancer: targeting the β-catenin pathway via microbiota -modulated miRNAs

Colorectal cancer (CRC) is a significant problem with worldwide public health consequences. One key factor in the genesis and progression of CRC is the aberrant upregulation of the Wnt/β-catenin signaling pathway. Inhibitors designed to target β-catenin directly have not been effective in clinical t...

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Библиографические подробности
Главные авторы: Rajkumar Prabhakaran, Ramkumar Muthu, Rajkumar Manickam, Venkatesh Subramanian, Karthikeyan Mahendran
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2026-01-01
Серии:Frontiers in Molecular Biosciences
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Online-ссылка:https://www.frontiersin.org/articles/10.3389/fmolb.2025.1736094/full
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