RNA helicase DDX5 regulates the translation and genomic replication of foot-and-mouth disease virus

ABSTRACT The internal ribosome entry site (IRES) is a cis-acting structural element found in many viral mRNAs, which mediates cap-independent translation by recruiting various RNA-binding proteins and IRES trans-acting factors (ITAFs). Foot-and-mouth disease virus (FMDV), a significant member of the...

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Hauptverfasser:	Jin'en Wu, Sahibzada Waheed Abdullah, Pinghua Li, Xuefei Wang, Mei Ren, Yuanyuan Huang, Xianglong Guo, Shiqi Sun, Huichen Guo
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology 2026-03-01
Schriftenreihe:	Journal of Virology
Schlagworte:	internal ribosome entry site (IRES) DDX5 foot-and-mouth disease virus (FMDV) IRES-driven translation replication
Online-Zugang:	https://journals.asm.org/doi/10.1128/jvi.01731-25
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