Estrogen Deficiency Impairs Osseointegration in Hypertensive Rats Even Treated with Alendronate Coated on the Implant Surface

Hypertension and estrogen deficiency can affect bone metabolism and therefore increase the risk of osseointegration. Antihypertensive drugs such as losartan not only control blood pressure but also enhance bone healing. In addition, alendronate sodium is widely used to treat postmenopausal osteoporo...

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Autori principali:	Gabriel Mulinari-Santos, Jaqueline Silva dos Santos, Igor Lebedenco Kitagawa, Fábio Roberto de Souza Batista, Paulo Roberto Botacin, Cristina Antoniali, Paulo Noronha Lisboa-Filho, Roberta Okamoto
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2023-09-01
Serie:	Journal of Functional Biomaterials
Soggetti:	bone losartan osseointegration alendronate spontaneously hypertensive rats
Accesso online:	https://www.mdpi.com/2079-4983/14/9/471
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